An international team of neuroscientists under leadership of Ed Lein and Hongkui Zeng worked on studies to map the cell types that make up the human brain. VU scientists Natalia Goriounova, Christiaan de Kock and Huib Mansvelder and their teams also contributed to this together with neurosurgeons from the VUmc.
With 750 kEUR funding from TKI, Hilgo Bruining and Klaus Linkenkaer-Hansen have teamed up with the company Clouds of Care in a public-private partnership to accelerate research and implementation of EEG analysis for precision medicine in patients with epilepsy or children with a neurodevelopmental disorder like autism.
The speed at which the human brain processes information is higher than in other animal species. Neuroscientist René Wilbers discovered that by examining millions of brain cells collected from a live sample of brain tissue.
Huib Mansvelder, professor and head of the department of Integrative Neurophysiology at VU Amsterdam, received the prestigious European Research Council Advanced Grant this week. This is the largest personal research grant in Europe.
The American National Institute of Health will fund new brain research of three CNCR researchers at VU Amsterdam through the so-called Brain Initiative programme. Brain research is desperately needed to better understand and treat brain diseases.
The performance of CNCR researchers Rachel Brouwer, Loek van der Kallen and Mahesh Karnani has been evaluated positively and we are happy to announce that they are rewarded a permanent employment contract.
The new joint degree program (linked to the Master of Neurosciences program at BETA-CNCR & VUmc) receives 6-year funding from the European Erasmus Mundus program of Erasmus+.
Rik van der Kant, Natalia Goriounova and Priyanka Rao-Ruiz, researchers at the Center for Neurogenomics & Cognitive Research at the Vrije Universiteit Amsterdam, have been awarded by the Dutch Research Council (NWO) with a Vidi grant worth 800,000 euros.
Dr. Christiaan de Kock awarded Open Competition ENW-M-2 grant (700k€) to study multisensory processing in primary visual cortex.
Teams at the VU Amsterdam, Heidelberg University, Center of Advanced European Studies and Research (Bonn) and Max Planck Institute for Neurobiology (Martinsried) achieve next step in understanding how sensory information is represented across different cell-types of primary somatosensory (barrel) cortex of behaving rats. Their findings were published in Communications Biology.
The group of Klaus Linkenkaer-Hansen (INF) established a method to estimate excitation/inhibition balance using the theory of critical brain dynamics. By teaming up with the group of Hilgo Bruining (Amsterdam UMC), the method is validated for physiological stratification of autism spectrum disorder.
Biomarker integration for better clinical decision making
Arthur-Ervin Avramiea, Richard Hardstone and colleagues from the team of Klaus Linkenkaer-Hansen (INF) publish in eLife that pre-stimulus phase and amplitude regulation of stimulus processing is maximized when neuronal networks operate in the critical state.
Development and modulation of mouse and human cortical circuitry
Natalia Goriounova published the association between large human pyramidal neurons that generate fast action potentials and intelligence in eLIFE
Joshua Obermayer and Tim Heistek publish their study on cholinergic regulation of lateral inhibition in human and mouse cortex in Nature Communications
Causes and consequences of disturbed brain ion and water homeostasis in the white matter disease MLC
Caffeine, adenosine and acetylcholine and neuronal function in the cortex, June 26, 2018
Inhibition in executive function neurocircuits in an autism model, and human neocortex, June 14, 2018
Collaboration between CNCR and VUmc published in Annals of Neurology
Filipa Teixeira Borges publishes her findings in Journal of Neuroscience
A functional dissection of human nicotinic receptor polymorphisms linked to
addiction and schizophrenia
The Metro Newspaper reports on Amber’s findings
Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human Neocortex
Optical Methods in Dendritic Physiology, December 22nd, 2017
Water and ion homeostasis in the developing brain: disease models impacting understanding of physiology
Teams at the VU Amsterdam, EPFL and Hebrew University of Jerusalem achieve next step in disentangling the neuronal circuitry in human neocortex.
Huib Mansvelder and his team receive 1.25 million dollar from the NIH for their research on human brain cells.
Organizational Principles of Human and Rodent Neocortex, March 20, 2017
First description of cholinergic modulation of long-term plasticity in human neocortex
On the 19th and 20th of May, our lab hosted the BACOFUN 2016 meeting with renowned keynote speakers including profs. Gordon Fishell, Adam Kepecs, Moritz Helmstaedter, Michael Stryker, Anthony Holtmaat, David Kleinfeld and Josh Huang.
Remco Klaassen’s and Jasper Stroeder’s work on the AMPA receptor auxiliary subunit Shisa6 appeared in Nature Communications
Hemanth Mohan and Thijs Verhoog published their paper reporting the first full quantitative neuronal morphologies of human pyramidal neurons including dendrites as well as axons.
Christiaan de Kock, Huib Mansvelder and collaborators publish two papers in Cerebral Cortex on the organizational principles of cortex in rat and human.
The 4-year PhD project is funded by a grant from the Netherlands Organization for Scientific Research (MaGW, NWO) to Klaus Linkenkaer-Hansen and "Research Talent" Arthur-Ervin Avramiea.
In a collaboration between researchers at KU Leuven and the Meredith group at the CNCR, a recent article in Nature Neuroscience shows developmental delays in cortical brain development prior to birth in a mouse model of the most common inherited form of intellectual disability and autism disorder, Fragile X syndrome.
