Jorim Tielbeek

Short CV

• Sept 2019 – now: Postdoc at the Complex Trait Genetics Lab, CNCR, Amsterdam Neuroscience Campus, VU University, Amsterdam (VCAS/VU Talentfonds 2019).
• Sept 2018 – Sept 2019: Postdoc at the Child and Adolescent Psychiatry Department, VU Medical Center Amsterdam
• June 2013 – Sept 2018: PhD student at the Child and Adolescent Psychiatry Department, VU Medical Center Amsterdam (NWO Research Talent Grant). Working visits at QIMR Berghofer, Brisbane, Australia (2014) and College of Criminology and Criminal Justice, Florida State University, United States (2015).
• Sep 2010 – Aug 2012: Master of Neurosciences (cum laude), VU University, Amsterdam.
• Sep 2008 – Aug 2010: VU University Honours Program
• Sep 2007 – Aug 2010: Bachelor in Biological Psychology, VU University, Amsterdam.
• Sep 2006 – Aug 2012: Bachelor in Criminology, VU University, Amsterdam.

Research

I am fascinated by the question why youngsters differ in their propensity to develop antisocial psychopathologies. To tackle this question I use a biosocial approach: incorporating both biological risk factors (i.e. genetic make-up, brain structure and function) and social factors (peer influences, childhood adversity). Given the typical low effect sizes found in these studies, larger samples are needed to achieve sufficient statistical power and thus collaboration is key. Hence I initiated the Broad Antisocial Behavior Consortium (BroadABC) with the mission to conduct genetic and gene-environment interaction analyses at a large scale on antisocial behaviour aimed at identifying pathways underlying antisocial behaviour.

Highlighted publications

Tielbeek, J. J., Medland, S. E., Benyamin, B., Byrne, E. M., Heath, A. C., Madden, P. A. F., … Verweij, K. J. H. (2012). Unraveling the Genetic Etiology of Adult Antisocial Behavior: A Genome-Wide Association Study. PLOS ONE, 7(10), e45086.O.

Tielbeek, J. J., Johansson, A., Polderman, T. J., Rautiainen, M. R., Jansen, P., Taylor, M., … Popma A., Medland S.E., Posthuma, D. (2017). Genome-wide association studies of a broad spectrum of antisocial behavior. JAMA Psychiatry, 74, 1242-1250.

Tielbeek, J. J., Karlsson Linner, R., Beers, K., Posthuma, D., Popma, A., & Polderman, J. C. (2016). Meta-analysis of the serotonin transporter promoter variant (5-HTTLPR) in relation to adverse environment and antisocial behavior. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, (171), 748-760.

Jorim J. Tielbeek, Jacqueline M. Vink, Tinca J.C. Polderman, Arne Popma, Danielle Posthuma, & Karin J.H. Verweij (2018. Genetic correlation of antisocial behavior with alcohol, nicotine, and cannabis use. Drug and Alcohol Dependence, 187, 296-299. O.

Tielbeek, J.J., Barnes, J., Popma, A., Polderman, T., Lee, J., Perry, J., … Boutwell, B. (2018). Exploring the genetic correlations of antisocial behavior and life history traits. Britisch Journal of Psychiatry Open, 4(6), 467-470. doi:10.1192/bjo.2018.63. O. 

Jorim J Tielbeek; Al-Itejawi*, Zeineb; Zijlmans, Josjan; Polderman, Tinca JC; Buckholtz, Joshua W; Popma, Arne (2016). The impact of chronic stress during adolescence on the development of aggressive behavior: A systematic review on the role of the dopaminergic system in rodents. Neuroscience & Biobehavioral Reviews. 91.10.1016/j.neubiorev.2016.10.009.

Barnes, J.C., Tielbeek, J.J., (2018). The Behavioral Genetics of Aggression and Violent Behavior. The Cambridge Handbook of Violent Behavior and Aggression, 2nd edition, Cambridge University Press, Cambridge.