King CR, A A Quadros AR, Chazeau A, Saarloos I, van der Graaf AJ, Verhage M, Toonen RF. Fbxo41 Promotes Disassembly of Neuronal Primary Cilia. (2019) Scientific Reports.
Meijer M, Rehbach K, Brunner JW, Classen JA, Lammertse HCA, van Linge LA, Schut D, Krutenko T, Hebisch M, Cornelisse LN, Sullivan PF, Peitz M, Toonen RF, Brüstle O, Verhage M. A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons. (2019) Cell Reports 27(7):2199-2211.
Persoon CM, Moro A, Nassal JP, Farina M, Broeke JH, Arora S, Dominguez N, van Weering JR, Toonen RF#, Verhage M#. Pool size estimations for dense-core vesicles in mammalian CNS neurons. (2018) EMBO J. 37(20).
Emperador-Melero J, Huson V, van Weering J, Bollmann C, Fischer von Mollard G, Toonen RF#, Verhage M#. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. (2018) Nature Communications 9(1):3421.
Kovacevic J, Maroteaux G, Schut D, Loos M, Dubey M, Pitsch J, Remmelink E, Koopmans B, Crowley J, Cornelisse LN, Sullivan PF, Schoch S, Toonen RF, Stiedl O, Verhage M. Protein instability, haploinsufficiency, and cortical hyper-excitability underlie STXBP1 encephalopathy. (2018) Brain 141(5):1350-1374.
van Keimpema L, Kooistra R, Toonen RF#, and Verhage M#. CAPS-1 requires its C2, PH, MHD1 and DCV domains for dense core vesicle exocytosis in mammalian CNS neurons. (2017) Scientific Reports 7(1):10817.
Schmitz SK, King C, Kortleven C, Huson V, Kroon T, Kevenaar JT, Schut D, Saarloos I, Hoetjes JP, de Wit H, Stiedl O, Spijker S, Li KW, Mansvelder HD, Smit AB, Cornelisse LN, Verhage M, Toonen RF. Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1. (2016) EMBO J. 35(11):1236-50
Farina M, van de Bospoort R, He E, Persoon CM, van Weering JR, Broeke JH, Verhage M, Toonen RF. CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons. (2015) eLife doi: 10.7554/eLife.05438
Cijsouw T, Weber JP, Broeke JH, Broek JAC, Schut D, Kroon T, Saarloos I, Verhage M and Toonen RF. Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. (2014) J Cell Biol. 204 (5);759–775
Spangler SA, Schmitz SK, Kevenaar JT, de Graaff E, de Wit H, Demmers J, Toonen RF#, and Hoogenraad CC#. Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. (2013) J Cell Biol. 10;201(6):915-28
van de Bospoort R, Farina M, Schmitz SK, de Jong A, de Wit H, Verhage M, Toonen RF.
Munc13 controls the location and efficiency of dense-core vesicle release in neurons. (2012) J Cell Biol. 199(6):883-91.
de Wit, J, Toonen RF, and Verhage M. Matrix-dependent local retention of secretory vesicle cargo in cortical neurons. (2009) J Neurosci. 29, 23-37.
Verhage M, and Toonen RF. Munc18-1 in secretion: lonely Munc joins SNARE team and takes control. (2007) Trends in Neuroscience 30 (11): 564-572.
Toonen RF*, Wierda K*, de Wit H, Brussaard AB, Verhage M. Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity. (2007) Neuron 54(2):275-290.